posted
by Dr. Ramon Reyes, MD ∞🧩
Fuente: https://www.linkedin.com/feed/update/urn:li:activity:7108183149385314304/
Conclusión: La infusión de epinefrina se asoció con mayores probabilidades de un nuevo arresto prehospitalario en comparación con la norepinefrina, pero no hubo diferencias en la supervivencia neurointacta. Los hallazgos enfatizan la necesidad de realizar más ensayos controlados aleatorios sobre este tema. Para profundizar en la investigación y sus implicaciones, consulte el estudio completo: PDF
Which is better post-ROSC for OHCA.... Epinephrine or Norepinephrine?
A recent study titled "Prehospital Administration of Norepinephrine and Epinephrine for Shock after Resuscitation from Cardiac Arrest" was conducted by Emma Wender and a team from Seattle. Here are the key takeaways:
🔹 Study Overview:
‣ The research included OHCA cases in Seattle, WA from 2014-2021.
‣ Out of 451 OHCA patients with return of spontaneous circulation (ROSC) followed by vasopressor infusion:
◘ 253 (56%) received norepinephrine
◘ 198 (44%) received epinephrine
🔹 Key Findings:
‣ Patients on epinephrine were more likely to rearrest in the prehospital setting: 55% vs 25% for those on norepinephrine.
‣ After adjustment for various factors, the odds of rearrest for epinephrine patients were 3.28 times higher.
‣ The odds of having pulses upon hospital arrival were lower for the epinephrine group (OR 0.52).
‣ Overall survival to hospital discharge was 14%, with 10% having a favorable neurological outcome.
‣ No significant difference was found between the two groups in terms of survival or neurological outcome.
🔹 Conclusion:
Epinephrine infusion was associated with higher odds of prehospital rearrest compared to norepinephrine yet there was no difference in neuro-intact survival. The findings emphasize the need for further randomized controlled trials on this topic.
For a deeper dive into the research and its implications, check out the full study: PDF
