 |
| TRANEXAMIC ACID / ACIDO TRANEXAMICO |
Leer tema relacionado
Tema para ver con detenimiento y revisa, no creo sea concluyente, pero me llama la atención bastante
Prehospital Tranexamic Acid for Severe Trauma. June 2023
Conclusions: Among adults with major trauma and suspected trauma-induced coagulopathy who were being treated in advanced trauma systems, prehospital administration of tranexamic acid followed by an infusion over 8 hours did not result in a greater number of patients surviving with a favorable functional outcome at 6 months than placebo. (Funded by the Australian National Health and Medical Research Council and others; PATCH-Trauma ClinicalTrials.gov number, NCT02187120.).
Copyright © 2023 Massachusetts Medical Society.
https://pubmed.ncbi.nlm.nih.gov/37314244/
Abstracts
Adv Emerg Nurs J. 2014 Apr;36(2):123-31
Tranexamic Acid for trauma-related hemorrhage.Bailey AM, Baker SN, Weant KA
Abstract:
Trauma-related deaths represent a leading cause of mortality among persons younger than 45 years. A significant percentage of these are secondary to hemorrhage. In trauma, massive and rapid loss of blood creates an imbalance in hemostasis. Mainstays of resuscitation include surgical interventions, restoring intravascular volume, and pharmacologic interventions. Providers continue to search for improved pharmacologic options for achieving hemostasis. Tranexamic acid is an antifibrinolytic and inhibits fibrinolysis by blocking the lysine-binding sites on plasminogen. Tranexamic acid works to stabilize and inhibit the degradation of existing clots. Tranexamic acid has been prospectively proven to reduce mortality in trauma-related hemorrhage. Its use will likely expand into such areas as resuscitation and massive transfusion protocols and the prehospital setting. Therefore, it is critical for emergency medicine providers to be familiar with appropriate use of tranexamic acid in order to maximize efficacy and decrease the potential adverse events.
Tranexamic Acid for trauma-related hemorrhage
AirLink VitaLink able to administer Tranexamic Acid to trauma patients with severe bleeding while en route to the New Hanover Medical Center
By EMS1 Staff
Dr. Heston Lamar, the service's medical director, told WECT that "the body can lose its ability to clot blood after a major traumatic injury. TXA works to restore that process and improve a patient's outcome of survival when used within three hours of the incident."
Since Dec. 1, TXA, prominently known for its use to treat wounded soldiers with severe bleeding, can be administered to patients in transport to the New Hanover Regional Medical Center.
WECT talked to a spokesman for AirLink VitaLink Critical Care Transport team who explained, "Being able to take this drug [TXA] to the bedside and administer it there on scene to get the trauma center and ICU level care started earlier, the better off the patient outcomes are."
TXA has been administered inside the trauma centers for years. Recently, research on using TXA outside of the hospital was conducted.
Lamar said that tests showed TXA was highly effective in stabilizing patients before they arrived at the hospital. In addition to stocking TXA on the critical care helicopters and ambulances, the New Hanover Regional Medical Center is working on approval to stock county EMS ambulances with TXA.
From EMS1
Related: Español
Ácido Tranexámico mejora la mortalidad en el Trauma con Shock Hemorragico
EMERGENCY EDUCATIONAL TRAINING INSTITUTE |
EMERGENCY EDUCATIONAL TRAINING INSTITUTE
is a professional and International recognized continuing education provider. Todd Soard hase offered a wide range of courses to fulfill your needs since 1992 that includes CPR, ACLS, PALS, Trauma, EMT Refresher, and Paramedic Refresher, plus much more. We are an AHA Training Center and welcome qualified AHA instructors to be part of our family.
Todd Soard; 2016 EMS Educator of the Year. Awarded by the Florida Department of Health, Bureau of Emergency Medical Oversight
+1.754-900-1224
Location:
9900 W Sample Rd #203 Coral Springs FL 33065
- Tranexamic Acid for trauma-related hemorrhage; Bailey AM, Baker SN, Weant KA; Adv Emerg Nurs J. 2014 Apr;36(2):123-31
- Review of new topical hemostatic dressings for combat casualty care; Bennett BL, Littlejohn L; Mil Med. 2014 May;179(5):497-514
- Feasibility and transport of packed red blood cells into Special Forces operational conditions; Boscarino C, Tien H, Acker J, Callum J, Hansen AL, Engels P, Glassberg E, Nathens A, Beckett A; J Trauma Acute Care Surg. 2014 Apr;76(4):1013-9
- An evidence-based prehospital guideline for external hemorrhage control: American College of Surgeons Committee on Trauma; Bulger EM, Snyder D, Schoelles K, Gotschall C, Dawson D, Lang E, Sanddal ND, Butler FK, Fallat M, Taillac P, White L, Salomone JP, Seifarth W, Betzner MJ, Johannigman J, McSwain N Jr; Prehosp Emerg Care. 2014 Apr-Jun;18(2):163-73
- A Triple-Option Analgesia Plan for Tactical Combat Casualty Care: TCCC Guidelines Change 13-04; Butler FK, Kotwal RS, Buckenmaier CC 3rd, Edgar EP, O'Connor KC, Montgomery HR, Shackelford SA, Gandy JV 3rd, Wedmore IS, Timby JW, Gross KR, Bailey JA; J Spec Oper Med. 2014 Spring;14(1):13-25
- The effect of hemostatic dressings in a subclavian artery and vein transection porcine model; Cestero R, Song B; Naval Medical Research Unit San Antonio NAMRU-SA Final Report #2013-012
- Evaluation of 8.0-cm needle at the forth anterior axillary line for needle chest decompression of tension pneumothorax; Chang SJ, Ross SW, Kiefer DJ, Anderson WE, Rogers AT, Sing RF, Callaway DW; J Trauma Acute Care Surg. 2014 Apr;76(4):1029-34
- Fresh whole blood transfusion for combat casualty in austere combat environment; Cordova CB, Capp AP, Spinella PC; J Spec Oper Med. 2014 Spring;14(1):9-12
- Flail chest injuries: a review of outcomes and treatment practices from the National Trauma Data Bank; Dehghan N, de Mestral C, McKee MD, Schemitsch EH, Nathens A; J Trauma Acute Care Surg. 2014 Feb;76(2):462-8
- An update on out-of-hospital airway management practices in the United States; Diggs LA, Yusuf JE, De Leo G; Resuscitation. 2014 Mar 15. [Epub ahead of print]
- Fluid resuscitation: less is more; Dries D; Crit Care Med. 2014 Apr;42(4):1005-6
- A comparison of conventional tube and EndoFlex tube for tracheal intubation in patients with a cervical spine immobilization; Gaszynska E, Stankiewicz-Rudnicki M, Wieczorek A, Gaszynski T; Scand J Trauma Resusc Emerg Med. 2014 Nov 22;21-79
- Prehospital emergency care: evaluation of the junctional emergency tourniquet tool with a perfused cadaver model; Gates KS, Baer L, Holcomb JB; J Spec Oper Med. 2014 Spring;14(1):40-4
- The lethal triad. Hypothermia, acidosis & coagulopathy create a deadly cycle for trauma patients; Gerecht R; JEMS. 2014 Apr;39(4):56-60
- Comparison of self-efficacy and its improvement after artificial simulator or live animal model emergency procedure training; Hall AB, Riojas R, Sharon D; Mil Med. 2014 Mar;179(3):320-3
- Needle thoracentesis decompression: observations from postmortem computed tomography and autopsy; Harcke HT, MAbry RL, Mazuchowski EL; J Spec Oper Med. 2014 Winter;l3(4):53-8
- Does the use of tranexamic acid improve trauma mortality?; Harvey V, Perrone J, Kim P; Ann Emerg Med. 2014 Apr;63(4):460-2
- Criminal gunshot wound and iatrogenic tension pneumothorax detected by post-mortem computed tomography; Hasegawa I, Heinemann A, Tzikas A, Vogel H, Puschel K; Leg Med (Tokyo). 2014 May;16(3):154-6
- Prehospital use of plasma: the blood bankers' perspective; Hervig T, Doughty H, Ness P, Badloe JF, Bersus Ok, Glassbuerg E, Heier HE; Shock. 2014 May;41 Suppl 1:39-43
- In-flight risk of venous thromboembolism and use of tranexamic acid in trauma patients; Hoffmann C, Falzone E, Donat A, Leclerc T, Donat N, Tourtier JP; Air Med J. 2014 Mar-Apr;33(2):48
- Optimal trauma resuscitation with plasma as the primary resuscitative fluid: the surgeon's perspective; Holcomb JB, Pati S; Hematology Am Soc Hematol Educ Program. 2013;2013:656-9. doi:10.1182/asheducation-2013.1.656
- Hartford Consensus: a call to action for THREAT, a medical disaster preparedness concept; Jacobs LM, Wade D, McSwain NE, Butler FK, Fabbri W, Eastman A, Conn A, Burns KJ; J Am Coll Surg. 2014 Mar;218(3):467-75. doi: 10.16/j.jamcollsurg.2013.12.009. Epub 2013 Dec 14
- Effects of intraosseous and intravenous administration of Hextend on time of administration and hemodynamics in a Swine model; Johnson D, Dial J, Ard J, Yourk T, Burke E, Paine C, Gegel B, Burgert J; J Spec Oper Med. 2014 Spring;14(1):79-85
- Evaluation of the efficacy and safety of tranexamic acid for reducing blood loss in bilateral total knee arthroplasty; Karam JA, Bloomfield MR, Dilorio TM, Irizarry AM, Sharkey PF; J Arthroplasty. 2014 Mar;29(3):501-3
- Simple thoracostomy. Moving beyond needle decompression in traumatic cardiac arrest; Karrer A, Monroe BJ, Gleisberg GR, Cosper J, Kimmel K, Escott ME; JEMS. 2014 Apr;39(4):26-32
- Hemostatic resuscitation is neither hemostatic nor resuscitative in trauma hemorrhage; Khan S, Brohi K, Chana M, Raza I,k Stanworth S, Gaarder C, Davenport R; International Trauma Research Network (INTRN); J Trauma Acute Care Surg. 2014 Mar;76(3):561-7
- Reply to Letter: Tactical combat casualty care rules applied to civilian traumatic cardiopulmonary resuscitation: Synergism of civilian and military trauma management; Kleber C, Giesecke MT, Kollow G, Haas NP, Buschmann CT; Resuscitation. 2014 Jun;85(6):e87-8
- Comparison of the hemostatic efficacy of low-volume lyophilized plasma reconstituted using sterile water, lactated Ringer's, normal saline, and Hextend solutions; Lee TH, McCully SP, McCully BH, Sands C, Hampton DA, Louis SG, Rick B, Anderson N, Differding J, Schreiber MA; J Trauma Acute Care Surg. 2014 Feb;76(2):264-1
- The effect of tranexamic acid in blood loss and transfusion volume in adolescent idiopathic scoliosis surgery: a single-surgeon experience; Lykissas MG, Crawford AH, Chan G, Aronson LA, Al-Sayyad MJ; J Child Orthop. 2013 Jun;7(3):245-9
- Challenges to improving combat casualty survival on the battlefield; Mabry RL, Delorenzo R; Mil Med. 2014 May;179(5):477-82
- Airway management and out-of-hospital cardiac arrest outcome in the CARES registry; McMullan J, Gerecht, Bonomo J, Robb R, McNally B, Donnelly J, Wang HE, CARES Surveillance Group; Resuscitation. 2014 May;85(5):617-22
- Glasgow Coma Scores, early opioids, and posttraumatic stress disorder among combat amputees; Melcer T, Walker J, Sechriest VF 2nd, Lebedda M, Quinn K, Galarneau M; J Trauma Stress. 2014 Apr;27(2):152-9
- Evaluation of Fluid Bolus Administration Rates Using Ruggedized Field Intravenous Systems; Morgan TR; Wilderness Environ Med. 2014 Mar 12 [Epub ahead of print]
- Assessment of hypovolaemic shock at scene: is the PHTLS classification of hypovolaemic shock really valid?; Mutschler M, Nienaber U, Münzberg M, Fabian T, Paffrath T, Wölfl C, Bouillon B, Maegele M; Emerg Med J. 2014 Jan;31(1):35-40
- Comparison of bag-valve-mask hand-sealing techniques in a simulated model; Otten D, Liao MM, Wolken R, Douglas IS, Mishra R, Kao A, Barrett W, Drasler E, Byyny RL, Haukoos JS; Ann Emerg Med. 2014 Jan;63(1):6-12.e3
- Tactical Combat Casualty Care rules applied to civilian traumatic cardiopulmonary resuscitation; Pasquier P, Carbonnel N, Bensalah M, et al; Resuscitation 2014;Epub ahead of print
- The traffic light bougie: a study of a novel safety modification; Paul A, Gibson AA, Robinson OD, Koch J; Anaesthesia. 2014 Mar;69(3)
- Self-expanding foam for prehospital treatment of severe intra-abdominal hemorrhage: dose finding study; Peev MP, Rago A, Hwabejire JO, Duggan MJ, Beagle J, Marini J, Zugates G, Busold R, Freyman T, Velmahos GS, Demoya MA, Yeh DD, Fagenholz PJ, Sharma U, King DR; J Trauma Acute Care Surg. 2014 Mar;76(3):619-23
- Interrupting My Shift: Disaster Preparedness and Response; Pole T, Marcozzi D, Hunt RC; Ann Emerg Med. 2014 May;63(5):584-588
- Ketamine; Quibell R, Prommer EE, Mihalyo M, Twycross R, Wilcock A; J Pain Symptom Manage. 2011 Mar;41(3):640-9;
- The humble bougie…forty years and still counting?; Rai MR; Anaesthesia. 2014 Mar;69(3):199-203
- Increasing trauma deaths in the United States; Rhee P, Joseph B, Pandit V, Aziz H, Vercruysse G, Kulvatunyou N, Friese RS; Ann Surg. 2014 Mar 19
- Case records of the Massachusetts General Hospital. Case 15-2014. A man in the military who was injured by an improvised explosive device in Afghanistan; Sheridan RL, Shumaker PR, King DR, Wright CD, Itani KM, Cancio LC; N Engl J Med. 2014 May 15;370(20):1931-40
- Auto-transfusion tourniquets: the next evolution of tourniquets; David H Tang, Bohdan T Olesnicky, Michael W Eby, Lawrence E Heiskell; Open Access Emergency Medicine Dovepress 2013; 13 DEC 2014 Epub ahead of print
- Prehospital risk factors of mortality and impaired consciousness after severe traumatic brain injury: an epidemiological study; Tohme S, Delhumeau C, Zuercher M, Haller G, Walder B; Scand J Trauma Resusc Emerg Med. 2014 Jan 7;22:1
- A comparison of ketamine and morphine analgesia in prehospital trauma care: a cluster randomized clinical trial in rural Quang Tri province, Vietnam; Tran KP, Nguyen Q, Truong XN, Le V, Le VP, Mai N, Husum H, Losvik OK; Prehosp Emerg Care. 2014 Apr-Jun;18(2):257-64
- Risk Factors for Hypothermia in EMS-treated Burn Patients; Weaver MD, Rittenberger JC, Patterson PD, McEntire SJ, Corcos AC, Ziembicki JA, Hostler D; Prehosp Emerg Care. 2014 Jan 24. [Epub ahead of print]
- Battlefield administration of tranexamic acid by combat troops: a feasibility analysis; Wright C; J R Army Med Corps. 2013 Oct 23
- Physician roles in tactical emergency medical support: the first 20 years; Young JB, Sena MJ, Galante JM; J Emerg Med. 2014 Jan;46(1):38-45
Le puede interesarÁcido Tranexámico ATX. (TRANEXAMIC ACID TXN) Beneficios en el Trauma con Shock Hemorrágico. EMSWORLD
https://emssolutionsint.blogspot.com/2014/12/acido-tranexamico-mejora-la-mortalidad.html
Tranexamic Acid for trauma-related hemorrhage TXA
https://emssolutionsint.blogspot.com/2014/12/txa-use-approved-for-nc-critical-care.html
TXA / ATX Acido Tranexámico en Pacientes con Trauma Pediátricos
https://emssolutionsint.blogspot.com/2021/06/txa-atx-acido-tranexamico-en-pacientes.html
Acido Tranexamico (TXA) Intramuscular IM vs IV / Tranexamic acid (TXA) Intramuscular IM vs IV
https://emssolutionsint.blogspot.com/2023/04/tranexamic-acid-txa-intramuscular-im-vs.html
Grupo en TELEGRAM Sociedad Iberoamericana de Emergencias
https://t.me/joinchat/GRsTvEHYjNLP8yc6gPXQ9Q
Le puede interesar
Ácido Tranexámico ATX. (TRANEXAMIC ACID TXN) Beneficios en el Trauma con Shock Hemorrágico. EMSWORLD
https://emssolutionsint.blogspot.com/2014/12/acido-tranexamico-mejora-la-mortalidad.html
Tranexamic Acid for trauma-related hemorrhage TXA
https://emssolutionsint.blogspot.com/2014/12/txa-use-approved-for-nc-critical-care.html
TXA / ATX Acido Tranexámico en Pacientes con Trauma Pediátricos
https://emssolutionsint.blogspot.com/2021/06/txa-atx-acido-tranexamico-en-pacientes.html
Acido Tranexamico (TXA) Intramuscular IM vs IV / Tranexamic acid (TXA) Intramuscular IM vs IV
https://emssolutionsint.blogspot.com/2023/04/tranexamic-acid-txa-intramuscular-im-vs.html
Grupo en TELEGRAM Sociedad Iberoamericana de Emergencias
https://t.me/joinchat/GRsTvEHYjNLP8yc6gPXQ9Q
Balística de las heridas: introducción para los profesionales de la salud, del derecho, de las ciencias forenses, de las fuerzas armadas y de las fuerzas encargadas de hacer cumplir la ley http://emssolutionsint.blogspo
Guía para el manejo médico-quirúrgico de heridos en situación de conflicto armado by CICR http://emssolutionsint.blogspo
CIRUGÍA DE GUERRA TRABAJAR CON RECURSOS LIMITADOS EN CONFLICTOS ARMADOS Y OTRAS SITUACIONES DE VIOLENCIA VOLUMEN 1 C. Giannou M. Baldan CICR http://emssolutionsint.blogspo
Manual Suturas, Ligaduras, Nudos y Drenajes. Hospital Donostia, Pais Vasco. España http://emssolutionsint.blogspo
Manual CIERRE DE HERIDAS by ETHICON http://emssolutionsint.blogspo
Manual de suturas. Menarini http://emssolutionsint.blogspo
Técnicas de Suturas para Enfermería ASEPEYO y 7 tipos de suturas que tienen que conocer estudiantes de medicina http://emssolutionsint.blogspo
Cuaderno Enfermero.Cirugia Menor Heridas Suturas http://emssolutionsint.blogspo
Manual Práctico de Cirugía Menor. Grupo de Cirugia Menor y Dermatologia. Societat Valenciana de Medicina Familiar i Comunitaria http://emssolutionsint.blogspo
Protocolo de Atencion para Cirugia. Ministerio de Salud Publica Rep. Dominicana. Marzo 2016 http://emssolutionsint.blogspo
Manual de esterilización para centros de salud. Organización Panamericana de la Salud http://emssolutionsint.blogspo
Curso TECC by C-TECC TACTICAL EMERGENCY CASUALTY CARE . ESPAÑA http://emssolutionsint.blogspot.co.uk/2017/09/curso-tecc-espana-28-septiembre-2017.html
Saber mas sobre @TACMEDEspaña
TACTICAL MEDICINE TACMED España by EMS Solutions International
http://emssolutionsint.blogspot.co.uk/2017/09/tactical-medicine-tacmed-espana-by-ems.html
Por favor compartir nuestras REDES SOCIALES @DrRamonReyesMD, así podremos llegar a mas personas y estos se beneficiarán de la disponibilidad de estos documentos, pdf, e-book, gratuitos y legales..
Grupo Biblioteca/PDFs gratis en Facebook
https://www.facebook.com/
Facebook
Pinterest
Twitter
Blog
Gracias a todos el Canal somos mas de 1000 participantes en WhatsApp. Recordar este es un canal y sirve de enlace para entrar a los tres grupos; TACMED, TRAUMA y Científico. ahí es que se puede interactuar y publicar. Si le molestan las notificaciones, solo tiene que silenciarlas y así se beneficia de la informacion y la puede revisar cuando usted así lo disponga sin el molestoso sonido de dichas actualizaciones, Gracias a todos Dr. Ramon Reyes, MD Enlace al
Enlace a TACMED en WhatsApp https://chat.
Enlace a TRAUMA en WhasApp https://chat.whatsapp.
Enlace a Científico https://chat.
TELEGRAM Emergencias https://t.me/+sF_-
TELEGRAM TACMED https://t.me/CIAMTO
